News from Dr. Baum about promising new treatments:

I am having success with treatment of ALS, and Parkinson disease using IV Stem Cells. The Stem Cells are taken from the patients Fat, Bone marrow and vascular tree. The process takes all day. The improvements are remarkable. If any patients are afflicted with the diseases as mention contact my office for a consultation. ALS and Parkinson diseases can be halted and improved. I have patients with these diseases that will be happy to talk with you.

LOGIQ S8 Ultrasound Ergonomics Video

Offering an excellent blend of economics and ergonomics, the LOGIQ S8 is designed for both workflow convenience and user comfort. Form and function in balanced harmony. (more…)

Human Pluripotent Stem Cell-Derived Neurons Resistant

APP Processing in Human Pluripotent Stem Cell-Derived Neurons Is Resistant to NSAID-Based γ-Secretase Modulation

Increasing evidence suggests that elevated Aβ42 fractions in the brain cause Alzheimer’s disease (AD).

Although γ-secretase modulators (GSMs), including a set of nonsteroidal anti-inflammatory drugs (NSAIDs), were found to lower Aβ42 in various model systems, NSAID-based GSMs proved to be surprisingly inefficient in human clinical trials. Reasoning that the nonhuman and nonneuronal cells typically used in pharmaceutical compound validation might not adequately reflect the drug responses of human neurons, we used human pluripotent stem cell-derived neurons from AD patients and unaffected donors to explore the efficacy of NSAID-based γ-secretase modulation. We found that pharmaceutically relevant concentrations of these GSMs that are clearly efficacious in conventional nonneuronal cell models fail to elicit any effect on Aβ42/Aß40 ratios in human neurons. Our work reveals resistance of human neurons to NSAID-based γ-secretase modulation, highlighting the need to validate compound efficacy directly in the human cell type affected by the respective disease.

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Dr. Baum on Fox Television

Watch the video! >>> Fox Sports Network showing Dr. Baum administering STEM CELLS to Diego Sanchez UFC fighter and the interview. (more…)

The Future of Multiple Sclerosis Treatment

How Stem Cell Research Could Help Cure MS Symptoms
By Dorothy Foltz-Gray, Special to Lifescript (more…)

The Science of Mesenchymal Stem Cells and Regenerative Medicine

– Arnold Caplan PhD
Seven Part Video Series, all presented conveniently here. (more…)

Dramatic HIV News

LONDON (Reuters) – Two men with HIV have been off AIDS drugs for several months after receiving stem-cell transplants for cancer that appear to have cleared the virus from their bodies, researchers reported on Wednesday.

Both patients, who were treated in Boston and had been on long-term drug therapy to control their HIV, received stem-cell transplants after developing lymphoma, a type of blood cancer.

Lead (Pb) is an important environmental contaminant due to its widespread use over many centuries.

While it affects primarily every organ system of the body, the most pernicious effects of Pb are on the central nervous system leading to cognitive and behavioral modification. Despite decades of research, the mechanisms responsible for Pb toxicity remain poorly understood. (more…)

Alterations of Neuromuscular Function after the World’s Most Challenging Mountain Ultra-Marathon

We investigated the physiological consequences of the most challenging mountain ultra-marathon (MUM) in the world: a 330-km trail run with 24000 m of positive and negative elevation change. (more…)

The new pluripotent cells could prove a boon to regenerative medicine

Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells that are easily derived from fat tissue and are able to differentiate into virtually every cell type in the human body without genetic modification. (more…)